Bio-Ingénierie

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Publications scientifiques
2023

Articles

Opening the black box of traumatic brain injury: a holistic approach combining human 3D neural tissue and an in vitro traumatic brain injury induction device
(2023)
Frontiers in Neuroscience 17: 1189615.
2022

Articles

Reliability Study of a New Electromechanical Device Designed to Measure the Relative Dorsal Mobility of the First Ray of the Foot
Reymond N., Praz Q., Schoinas S., Sockalingam N., Acker A., Dubois-Ferrière V., Passeraub P., Assal M.
(2022)
Open Journal of Orthopedics 12: 383-392.
The Role of Interstitial Fluid Pressure in Cerebral Porous Biomaterial Integration
Bonini F., Mosser S., Mor F.M., Boutabla A., Burch P., Béduer A., Roux A., Braschler T.
(2022)
Brain Sciences 12, 417.
Statistical distortion of supervised learning predictions in optical microscopy induced by image compression
Pomarico E., Schmidt C., Chays F., Nguyen D., Planchette A., Tissot A., Roux A., Pagès S., Batti L., Clausen C., Lasser T., Radenovic A., Sanguinetti B., Extermann J.
(2022)
Scientific Reports 12, 3464.

Actes de conférences

Point-of-care device for assessing male fertility in animals through measurement of sperm concentration and motility
Najdenovska E., Dutoit F., Gomez Baisac L., Karlova Y., Karlov A., Roux A., Cuisenaire O., Raileanu L.
(2022)
Reproduction in Domestic Animals 57(S4): 82-83, Special Issue: Proceedings of the 25th Annual Conference of the European Society for Domestic Animal Reproduction (ESDAR), Thessaloniki, Greece, 28.09.-02.10.2022.
2021

Articles

Pad-Printing as a Fabrication Process for Flexible and Compact Multilayer Circuits
(2021)
Sensors, 21, 6802.
The interest of 100 versus 200 Hz tetanic stimulations to quantify low levels of residual neuromuscular blockade with mechanomyography: a pilot study
Dubois P.E., Mitchell J., Regnier M., Passeraub P., Moreillon F., d'Hollander A.A.
(2021)
Journal of Clinical Monitoring and Computing, published online.
100 Hz-5 s tetanic stimulation to illustrate the presence of “residual paralysis” co-existing with accelerometric 0.90 train-of-four ratio - A proof-of-concept study
Debaene B., Frasca D., Moreillon F., D'Hollander A.A.
(2021)
Anaesthesia Critical Care & Pain Medicine 40(4): 100903, published online.
SpikeOnChip : A Custom Embedded Platform for Neuronal Activity Recording and Analysis
Wertenbroek R., Thoma Y., Mor F.M., Grassi S., Heuschkel M., Roux A., Stoppini L.
(2021)
IEEE Transactions on Biomedical Circuits and Systems, Epub ahead of print. 
Blood–Brain Barrier Dynamic Device with Uniform Shear Stress Distribution for Microscopy and Permeability Measurements
Choublier N., Müller Y., Gomez Baisac L., Laedermann J., de Rahm C., Declèves X., Roux A.
(2021)
Applied Sciences 11, 5584.
Mass Generation, Neuron Labelling and 3D Imaging of Minibrains
S. Govindan, L. Batti, S. F. Osterop, Stoppini L., Roux A.
(2021)
Frontiers in Bioengineering and Biotechnology 8:582650.

Actes de conférences

Low-cost toxicogenomic profiling of Human iPSC derived minibrain reveals key adverse outcome pathways
Govindan S., Stoppini L., Roux A.
(2021)
Toxicology Letters 350: S126-S127, Abstract book of the EUROTOX virtual congress, 27.09.-01.10.2021.
Quantifying the Effect of Image Compression on Supervised Learning Tasks in Microscopy
Pomarico E., Schmidt C., Nguyen D., Planchette A., Roux A., Pagès S., Batti L., Clausen C., Lasser T., Radenovic A., Sanguinetti B., Extermann J.
(2021)
Focus on Microscopy 2021, online conference, 28.-31.03.2021.
2020

Actes de conférences

Portable tool for analyzing male fertility based on the measurement of sperm concentration and mobility
Nogueira T., Gomez Baisac L., Najdenovska E., Dutoit F., Karlova Y., Karlov A., Cuisenaire O., Raileanu L.E., Roux A.
(2020)
Swiss Symposium in Point-of-Care Diagnostics, Visp, 29.10.2020.
Towards a cheap, batteryless, wireless threshold temperature detector
(2020)
IEEE International Symposium on Antennas and Propagation and North American Radio Science Meeting, Montreal, Canada, 05-10.07.2020.

Articles

Soft Printable Electrode Coating for Neural Interfaces
Shur M., Fallegger F., Pirondini E., Roux A., Bichat A., Barraud Q., Courtine G., Lacour S. P.
(2020)
ACS Applied Bio Materials 3: 4388-4397.
Fabrication and Characterization of a Flexible Fluxgate Sensor with Pad-Printed Solenoid Coils
(2020)
Sensors, 20, 2275.
2019

Articles

A versatile robotic platform for the design of natural, three-dimensional reaching and grasping tasks in monkeys
Barra B., Badi M., Perich M.G., Conti S., Mirrazavi Salehian S.S., Moreillon F., Bogaard A., Wurth S., Passeraub P., Milekovic T., Billard A., Micera S., Capogrosso M.
(2019)
Journal of Neural Engineering 17(1): 016004.
Human Neural Organoids for Studying Brain Cancer and Neurodegenerative Diseases
Cosset E., Locatelli M., Marteyn A., Lescuyer P., Dall Antonia F., Mor F., Preynat-Seauve O., Stoppini L., Tieng V.
(2019)
Journal of Visualized Experiments 148, e59682.

Actes de conférences

Automatization of membrane contactors and applications for the management of dissolved gases in wines
Schönenberger P., Ducruet J., Pernet A., Marsan F., Bach B., Passeraub P., Zufferey D., Vorlet O.
(2019)
BIO Web of Conf. 15: 02037, 42nd World Congress of Vine and Wine OIV, Geneva, 15.-19.07.2019.
An electrostimulation cell device with patterned TiO2:Nb thin films as bio-electrodes
Jobin M., Pellodi C., Sandu C., Benvenutti G., Sandoz A., Stoppini L.
(2019)
TechConnect Briefs 2019:419-422, World Innovation Conference & Exposition, Boston, MA, 17.-19.06.2019.
2018

Articles

Development and Characterization of PEDOT:PSS/Alginate Soft Microelectrodes for Application in Neuroprosthetics
Ferlauto L., D’Angelo A.N., Vagni P., Airaghi Leccardi M.J.I., Mor F., Cuttaz E.A., Heuschkel M., Stoppini L.
(2018)
Frontiers in Neuroscience 12:648.
A VP1 mutation acquired during an enterovirus 71 disseminated infection confers heparan sulfate binding ability and modulates ex vivo tropism
Tseligka E. D., Sobo K., Stoppini L., Cagno V., Abdul F., Piuz I., et al.
(2018)
PLOS Pathogens 14(8): e1007190.
Congrès & conférences
2023

Organisation

TEDD Visit: Campus Biotech
Co-organisation de l'événement, visite du labo Tissue Engineering et mots de bienvenue et de clôture, Campus Biotech, Genève, 23.11.2023

Interventions orales et posters

Opening the black box of traumatic brain injury: a holistic approach combining human 3D neural tissue and an in vitro traumatic brain injury induction device
Swiss 3Rs Day, Lugano, 19.09.2023
Dynamic measurement of bio-impedance on in vitro breathable lung-on-chip system for long- term cell barrier integrity assessment
Bouiller G., Roux A.
5th Conference on Impedance-Based Cellular Assays (IBCA 2023), Aachen, Germany, 04.09.2023 - 06.09.2023
Development of human 3D neural in vitro model to replace in vivo traumatic brain injury rodent model
Symposium on Alternative Methods in Scientific Research «The enormous potential of alternative models for future research», CMU, Genève, 10.07.2023
Microelectrode arrays for electrical monitoring of 3D engineered brain tissues at the air liquid interface (Poster)
Heuschkel M., Gomez Baisac L., Loussert-Fonta C., Stoppini L., Roux A.
MicroNanoFabrication Annual Review Meeting, EPFL Center of MicroNanoTechnology (CMi), Lausanne, 02.05.2023 poster_heuschkel_cmi_2023.pdf
2022

Interventions orales et posters

In vitro model to replace in vivo traumatic brain injury rodent model (Poster)
Swiss 3Rs Day, Bern, 11.10.2022
Human brain-on-a chip: an in vitro platform for drug discovery and toxicity screening
2nd Workshop on Next Generation Organ-on-Chips & Organoids, Geneva, 23.08.2022 - 24.08.2022
Point-of-care sperm concentration and motility measurements using a portable acquisition and processing device (Poster)
Cuisenaire O., Karlov A., Roux A., Raileanu L.E.
IEEE Engineering in Medicine and Biology Society, Glasgow, Scotland, 11.07.2022 - 15.07.2022
Development of TEER instrument to monitor lung-on-chip barrier integrity (Poster)
EUROoCS Conference, Grenoble, France, 04.07.2022 - 05.07.2022
In vitro Traumatic Brain Injury (TBI) model based on Human 3D neural tissues
EUROoCS Conference, Grenoble, France, 04.07.2022 - 05.07.2022
A MEA-based in vitro Traumatic Brain Injury Platform (Poster)
MEA-meeting, Tübingen, Germany, 01.07.2022
Development and implementation of TEER measurement instrument to assess cellular barrier integrity on a lung-on-chip (Poster)
LIVe 2022 - Lung in vitro event for innovative and predictive models, Nice, France, 13.06.2022 - 14.06.2022
Development and implementation of an automated lung cell cilia visualisation platform compatible with cell culture environment (Poster)
LIVe 2022 - Lung in vitro event for innovative and predictive models, Nice, France, 13.06.2022 - 14.06.2022
Smart Sensor Systems for Digital Health and Industry 4.0
Les microtechniques au service des sciences de la vie: le pari gagnant pour l'innovation, évenement de l'OPI, Campus Biotech, Genève, 14.04.2022
Amélioration des modèles in vitro de culture cellulaire grâce aux technologies développées dans le domaine de la bio-ingénierie
Les microtechniques au service des sciences de la vie: le pari gagnant pour l'innovation, évenement de l'OPI, Campus Biotech, Genève, 14.04.2022

Organisation

Les microtechniques au service des sciences de la vie: le pari gagnant pour l'innovation
Co-organisation de l'évenement en partenariat avec l'OPI - Office de Promotion des Industries et des Technologies, Campus Biotech, Genève, 14.04.2022
2021

Interventions orales et posters

Portable tool for analyzing male fertility based on the measurement of sperm concentration and motility (Poster)
Swiss symposium in Point-of-Care Diagnostics, Davos, 21.10.2021
Towards the development of basic technological bricks for a Traumatic Brain Injury diagnostic cartridge
Schoinas S., Mairiaux E., Saidy A., Passeraub P.
Swiss Symposium in Point-of-Care Diagnostics, Davos, 21.10.2021
Development of an in vitro Blood-Brain Barrier dynamic biochip with uniform shear stress repartition (Poster)
International symposium "Signal Transduction at the Blood-Brain Barriers", online, 22.09.2021 - 24.09.2021
A Novel Screening Platform for Electrophysiological Assessment of 3D Neural Tissues Derived from Human Pluripotent Stem Cells (Poster)
Biointerfaces International Zurich 2021 conference, online, 18.08.2021 - 19.08.2021
Development of a new perfusion system on Human in vitro Blood-Brain Barrier biochip for toxicity assessment (Poster)
European Organ-on-Chip Society (EurOoCS) annual meeting, online - Uppsala, Sweden, 01.07.2021 - 02.07.2021
Long-Term in vitro monitoring of electrophysiological activities at different levels from 3D neural tissues using Porous Flex-Strip MEAs
European Organ-on-Chip Society (EurOoCS) annual meeting, online - Uppsala, Sweden, 01.07.2021 - 02.07.2021
Brain-on-a-Chip for drug discovery and toxicology screening
Learn & Lunch - the monthly Campus Biotech get-together, online, 10.02.2021 https://www.youtube.com/watch?v=ovZlqFPWpJs
2020

Interventions orales et posters

Development of a new perfusion system on Human in vitro Blood-Brain Barrier biochip for toxicity assessment (Poster)
European Organ-on-Chip Society (EurOoCS) annual meeting, online - Uppsala, Sweden, 07.07.2020 - 09.07.2020 eposter_euroocs_bbb_biochip_roux_2020-07.pdf
A perfused Biochips for continuous electrophysiological monitoring of 3-D neural tissues derived from Human pluripotent stem cells (Poster)
European Organ-on-Chip Society annual meeting (EurOoCS), online - Uppsala, Sweden, 07.07.2020 - 09.07.2020 eposter_euroocs_stoppini_2020-07.pdf
Porous and flexible polyimide microelectrode arrays (Poster)
MicroNanoFabrication Annual Review Meeting, EPFL Center of MicroNanoTechnology (CMi), Lausanne, 05.05.2020
Traumatic Brain Injury Point-of-Care Multiplex in vitro Diagnostic Device
Chiollaz A.-C., Pankratova N., Mairiaux E., Azurmendi L., Krattinger L., Schoinas S., Passeraub P., Pfeifer M.E., Sanchez J.-C.
BRIDGE Discovery Networking Event, Bern, 20.02.2020
2019

Interventions orales et posters

Development of an in vitro model based on human neural cells to study neuroinflammation processes (Poster)
100 Years of Microglia, international symposium, Lausanne, 10.12.2019
Implementation of a perfusion system on Human BBB toxicity platform
SST (Société Suisse de Toxicologie) Annual Meeting 2019, Basel, 28.11.2019 - 29.11.2019
Theoretical and practical aspects of the trans-epithelial electrical resistance (TEER) and tissues interconnection
Altertox Workshop, Plan-les-Ouates, 14.11.2019 - 15.11.2019
Development of a perfusion biochip on Human in vitro BBB model
Conférence scientifique sur la barrière hémato-encéphalique, Paris, France, 08.11.2019
Development of a pad printing process for compact multilayers electronic circuits
Swiss ePrint 2019 – The Swiss Conference on Printed Electronics and Functional Materials, Fribourg, 24.09.2019 - 25.09.2019
Towards pad printed strain gauges
Swiss ePrint 2019 – The Swiss Conference on Printed Electronics and Functional Materials, Fribourg, 24.09.2019 - 25.09.2019
Development of a new automatic platform for continuous monitoring of the Cilia Beating Frequency (CBF) (Poster)
Roux A., Gomez Baisac L., Simonnet N., Huang X.-Y., Constant S., Stoppini L.
Swiss 3Rs Day «60 years of Replacement, Reduction and Refinement of Animal Experimentation», Bern, 02.09.2019
Porous and flexible polyimide microelectrode arrays (Poster)
MicroNanoFabrication Annual Review Meeting, EPFL Center of MicroNanoTechnology (CMi), Lausanne, 07.05.2019
2018

Interventions orales et posters

Brain on a chip and Geneva Array Technologies
3rd Wyss Center Investigator Meeting, Geneva, 06.12.2018
Human in vitro neurovascular unit model for neurotoxicity assessment
SCAHT Annual Research Meeting, Wangen an der Aare, 04.12.2018 - 05.12.2018
Development of an in vitro platform to test next neuroprobe generations (Poster)
Neuroprosthetic Symposium, Geneva, 21.11.2018
Theoretical and practical aspects of the Trans-Epithelial Electrical Resistance (TEER)
Altertox Academy on In Vitro Lung Models, Plan-les-Ouates, 15.11.2018 - 16.11.2018
Les enjeux de la digitalisation dans le domaine de la santé
Modération de la table ronde, Journée de la Recherche Ingénierie & Architecture HES-SO, Fribourg, 10.10.2018
Développer des tests in vitro des médicaments de demain
Journée de la Recherche Ingénierie & Architecture HES-SO, Fribourg, 10.10.2018
Tester des nouveaux traitements grâce à nos cellules souches ?
Official launch of Planète Santé, Genève, 06.10.2018
Advanced Lightsheet Imaging Center (ALICE)
Pagès S., Batti L., Voigt F., Reymond G., Brana C., Tissot A., Holtmaat A., Luscher C., Courtine G., Helmchen F., Moreillon F., Passeraub P., Donoghue J.
The 11th FENS Forum of Neuroscience, Berlin, Germany, 07.07.2018 - 11.07.2018
Development of an in vitro model of NanoNeurotoxicity using human 3D neural tissues: Functional assay using porous microelectrode array (Poster)
MEA Meeting 2018: 11th International Meeting on Substrate-Integrated Microelectrode Arrays, Reutlingen, Germany, 04.07.2018 - 06.07.2018
Polyimide-based 3D microelectrode arrays for in vitro testing of human 3D engineered neural tissues (Poster)
MEA Meeting 2018: 11th International Meeting on Substrate-Integrated Microelectrode Arrays, Reutlingen, Germany, 04.07.2018 - 06.07.2018
Mini-Brains on-a-Chip: 3D engineered nervous tissues derived from human stem cells for testing new generations of neural interfaces
Translational Neuroscience & Neuroengineering Workshop, Newport, USA, 04.06.2018
Ingénierie au service des Diagnostics Médicaux: Programme «Diagnostic BioChips»
Journée HES-SO Diagnostic Biochips organisée en collaboration avec la Fondation Inartis et la Health Valley Switzerland, Etoy, 18.05.2018
DIAGNOTOX – «Réalité augmentée» pour le monitorage et le test de toxicité in vitro (Poster et stand)
Journée HES-SO Diagnostic Biochips en collaboration avec la Fondation Inartis et la Health Valley Switzerland, Etoy, 18.05.2018 https://www.hes-so.ch/data/documents/Poster--Diagnostic-Biochips--DiagnoTox-9260.pdf
In vitro system for integrity assessment of biological barriers (Poster et stand)
Journée HES-SO Diagnostic Biochips en collaboration avec la Fondation Inartis et la Health Valley Switzerland, Etoy, 18.05.2018 https://www.hes-so.ch/data/documents/Poster--Diagnostic-Biochips--TEER-9248.pdf
In vitro neural tissue testing platform using Micro-Electrode Arrays (Poster et stand)
Journée HES-SO Diagnostic Biochips en collaboration avec la Fondation Inartis et la Health Valley Switzerland, Etoy, 18.05.2018 https://www.hes-so.ch/data/documents/Poster--Diagnostic-Biochips--mea-9256.pdf
Organ on chips (vidéo)
Journée HES-SO Diagnostic Biochips en collaboration avec la Fondation Inartis et la Health Valley Switzerland, Etoy, 18.05.2018 https://www.youtube.com/watch?v=mTnIOa1CWoo
TEER - Trans Epithelial/Endothelial Electric Resistance (vidéo)
Journée HES-SO Diagnostic Biochips en collaboration avec la Fondation Inartis et la Health Valley Switzerland, Etoy, 18.05.2018 https://www.hes-so.ch/fr/journee-diagnostic-biochips-11563.html
Your microsystems on a print (vidéo)
Journée HES-SO Diagnostic Biochips en collaboration avec la Fondation Inartis et la Health Valley Switzerland, Etoy, 18.05.2018 https://www.youtube.com/watch?v=TiSyifw6Kgw&feature=youtu.be
Porous and flexible polyimide microelectrode arrays (Poster)
MicroNanoFabrication Annual Review Meeting, EPFL Center of MicroNanoTechnology (CMi), Lausanne, 08.05.2018
Visual-ITF: Making anesthesia safer Precisely informing the anesthetist about curare effects and residues
Passeraub P., Moreillon F., d'Hollander A.
Geneva Health Forum, Precision Global Health in the Digital Age, Geneva, 10.04.2018 - 12.04.2018
Médecine préventive: comment sécuriser et améliorer les gestes médicaux grâce à Visual ITF, nouvel instrument dédié à l’anesthésie ?
Passeraub P., Moreillon F., Hollander A.
MEDI’NOV Connection 2018, Grenoble, France, 21.03.2018 - 22.03.2018
Salons et expositions
2022

2022

Salon ILMAC
Poster sur le stand BioAlps, Lausanne, 28.09.2022 - 29.09.2022
Salon EPHJ
Stand HES-SO - HEPIA, Palexpo, Genève, 14.06.2022 - 17.06.2022
2021

2021

Salon MecaPlasTronic Connection
Conférence thématique Plastronique: "Comment fabriquer des capteurs sans fil à faible coût grâce à la technologie 3D-MID?", Ainterexpo, Bourg-en-Bresse, France, 12.10.2021 - 13.10.2021
Salon MecaPlasTronic Connection
Stand HEPIA et atelier pratique, Ainterexpo, Bourg-en-Bresse, France, 12.10.2021 - 13.10.2021
Salon EPHJ
Pitch scientifique: Pourquoi les biologistes ont besoin de la microtechnique: Exemple des «Organs-on-Chip», Palexpo, Genève, 14.09.2021 - 17.09.2021 ephj2021_slides_roux.pdf
Salon EPHJ
Pitch scientifique: Avancée vers l'impression de microsystèmes écologiques par tampographie, Palexpo, Genève, 14.09.2021 - 17.09.2021 ephj2021_slides_passeraub.pdf
2019

2019

International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2019)
Stand HES-SO, Congress Center, Basel, 27.10.2019 - 31.10.2019
Salon EPHJ – EPMT – SMT
Pitch scientifique: «Mini-Brains on-a-Chip» - Plateforme pour le monitoring de tissus nerveux en culture, Palexpo, Genève, 20.06.2019
Salon EPHJ - EPMT - SMT
Stand HES-SO – MedTech, Palexpo, Genève, 18.06.2019 - 21.06.2019
2018

2018

COMPAMED
Stand HEPIA/HES-SO/BioAlps, Düsseldorf, Allemagne, 12.11.2018 - 15.11.2018
Journée de la Recherche Ingénierie & Architecture HES-SO
Stand «MEAZURE: Smart Petri Dish for drug development and toxicology studies», Fribourg, 10.10.2018
Salon Planète Santé
Gomez Baisac L., Macchi J., Kaltenrieder V., Roux A.
Stand «Meazure: développement d’une approche alternative in vitro plus prédictive car plus proches de la physiologie humaine», Genève, 04.10.2018 - 07.10.2018
Salon ILMAC
Stand «Perfused Human in vitro model to assess neurotoxicity», Lausanne, 03.10.2018 - 04.10.2018
Salon EPHJ - EPMT - SMT
Stand HES-SO – MedTech, Palexpo, Genève, 12.06.2018 - 15.06.2018
Salon EPHJ - EPMT - SMT
Pitch scientifique: Visual-ITF: making anesthesia safer, Palexpo, Genève, 12.06.2018 - 15.06.2018
Geneva Health Forum
Stand de présentation de projets, Genève, 10.04.2018 - 12.04.2018
MEDI’NOV Connection
Stand HEPIA, Grenoble, France, 21.03.2018 - 22.03.2018
Apparitions médias
2023

Presse

Entreprise Romande,
17.11.2023
Intervenant HEPIA : Luc Stoppini
2019

Télévision

TV5 Monde, 64' le monde en français, minute 19:50,
26.11.2019
Intervenant HEPIA : Adrien Roux

Presse

Simply Science, Portraits,
15.11.2019
Intervenant HEPIA : Loris Gomez Baisac
Le Temps,
20.05.2019
Intervenant HEPIA : Luc Stoppini

Radio

Radio Lac, Actualité,
18.06.2019
Intervenant HEPIA : Luc Stoppini
2018

Télévision

RTS, émission Le court du jour,
29.01.2018
Intervenant HEPIA : Luc Stoppini

Presse

PME Magazine,
01.05.2018
Intervenant HEPIA : Philippe Passeraub , Luc Stoppini