Genomics is the study by sequencing of the entire genome of an organism, while transcriptomics studies the expression of this genome and its interactions with its environment. Metagenomics allows the study of all the genomes of a community of prokaryotic and eukaryotic microorganisms in a given environment. Metabarcoding is characterised by the pre-amplification of barcodes (DNA fragments) before the sequencing stage in order to identify the desired species in an environment.
The applications proposed and carried out at HEPIA are in the field of the environment, ecology or agronomy. Companies can therefore benefit from a very wide range of services, such as: analysis of the microbiota of bee products (royal jelly, honey, bee bread, pollen), of fresh and fermented birch sap, of the microbiota of artificial human intestines, of the microbiota of soils after high-intensity steam treatment, monitoring of macrofauna or follow-up of certain species in high altitude ponds, or analysis of the diet of vertebrate species.
Simplified overview of the sample analysis process. Picture: J. Crovadore, HEPIA
Environmental DNA (eDNA) analysis by metabarcoding (LibelAlps Project / B. Oertli). Pictures: M. Lamouille-Hébert
Analysis and monitoring of the microbiota of the artificial human gut by metagenomics (GUTM project / W. Brück and F. Lefort). Picture: J. Crovadore, HEPIA
Project partner(s)
Project leader - team
Julien Crovadore
(HEPIA),
François Lefort
(HEPIA)
