As part of research into rare muscular diseases such as Duchenne muscular dystrophy (DMD) and centronuclear myopathies, laboratory mice are used to measure the evolution of muscular diseases and thus evaluate the efficacy of new or existing drug treatments, natural products, cellular therapies or experimental genetics.
The laboratory of Dr. Olivier Dorchies, from the FABIP Pharmaceutical Biochemistry Group at the Geneva School of Pharmacy, is studying these rare diseases.
One of the experiments, the «grip strength test», involves measuring the strength of a mouse pulling a grid, in order to estimate the state of the muscles as the disease progresses. In this context, we have developed an innovative system comprising a mechanical part, specific electronics and firmware, and appropriate visualization software.
UPSCALE User Interface (UI)
Welcome picture: UPSCALE Acquisition hardware
Project partner(s)
Project leader - team
Nicola Giandomenico
(HEPIA),
Bryan Musy
(HEPIA)