Jean-Noël Hyacinthe

Professeur HES associé

Filière Technicien en radiologie médicale

Téléphone de service : +41 22 388 56 00

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Profil

Projets Ra&D

Cibler l’AVC avec l’IRM hyperpolarisée

(2017 - En cours)

Jean-Noël Hyacinthe Lorenz Hirt (CHUV, Lausanne)

Thématique(s) et méthode(s): Vieillir en bonne santé, Pratiques professionnelles, Recherche clinique, Technologie de la santé

Publications

Evaluating the potential of hyperpolarised [1-13C] L-lactate as a neuroprotectant metabolic biosensor for stroke

Hyacinthe, J.-N., Buscemi, L., Lê, T. P., Lepore, M., Hirt, L., Mor, M.(2020). Scientific Reports, 10, 1-11.

Micron-sized PFOB liquid core droplets stabilized with tailored-made perfluorinated surfactants as a new class of endovascular sono-sensitizers for focused ultrasound thermotherapy

Desgranges, S., Lorton, O., Gui-Levy, L., Guillemin, P., Celicanin, Z., Hyacinthe, J.-N., Breguet, R., Crowe, L.A., Becker, C.D., Soulié, M., Taulier, N., Contino-Pépin, C., Salomir, R.(2019). Journal of Materials Chemistry B, 7(6)

Hybrid ultrasound-MR guided HIFU treatment method with 3D motion compensation

Celicanin, Z., Manasseh, G., Petrusca, L., Scheffler, K., Auboiroux, V., Crowe, L. A., Hyacinthe, J. N., Natsuaki, Y., Santini, F., Becker, C. D., Terraz, S., Bieri, O., Salomir, R.(2018). Magnetic Resonance in Medicine , 79(5), 2511-2523.

Molecular oxygen loading in candidate theranostic droplets stabilized with biocompatible fluorinated surfactants: Particle size effect and application to in situ(19)F MRI mapping of oxygen partial pressure

Lorton, O., Hyacinthe, J. N., Desgranges, S., Gui, L., Klauser, A., Celicanin, Z., Crowe, L. A., Lazeyras, F., Allemann, E., Taulier, N., Contino-Pepin, C., Salomir, R.(2018). Journal of Magnetic Resonance , 295, 27-37.

In vivo pink-beam imaging and fast alignment procedure for rat brain tumor radiation therapy

Nemoz, C., Kibleur, A., Hyacinthe, J. N., Berruyer, G., Brochard, T., Brauer-Krisch, E., Le Duc, G., Brun, E., Elleaume, H., Serduc, R.(2016). Journal of Synchrotron Radiation, 23(1), 339-43.

Correcting surface coil excitation inhomogeneities in single-shot SPEN MRI

Schmidt, R., Mishkovsky, M., Hyacinthe, J. N., Kunz, N., Gruetter, R., Comment, A., Frydman, L.(2015). Journal of Magnetic Resonance , 259, 199-206.

Photoinduced nonpersistent radicals as polarizing agents for X-nuclei dissolution dynamic nuclear polarization

Capozzi, A., Hyacinthe, J.-N., Cheng, T., Eichhorn, T. R., Boero, G., Roussel, C., van der Klink, J. J, Comment, A.(2015). The Journal of Physical Chemistry C, 119(39), 22632-22639.

Beyond spin exchange optical pumping: hyperpolarization of 129Xe via sublimation dynamic nuclear polarization

Hyacinthe, J.N., Capozzi, A., Comment, A.(2015). Hyperpolarized Xenon-129 Magnetic Resonance (Concepts, Production, Techniques and Applications)

Optimal glass-forming solvent brings sublimation dynamic nuclear polarization to129Xe Hyperpolarization biomedical imaging standards

Capozzi, A., Roussel, C., Comment, A., Hyacinthe, J. N.(2015). The Journal of Physical Chemistry C, 119(9), 5020-5025.

http://dx.doi.org/10.1021/jp5124053

Nouveaux horizons pour l’imagerie moléculaire

Hyacinthe, J.N.(2014). Planète Santé

Hyperpolarization without persistent radicals for in vivo real-time metabolic imaging.

Eichhorn, T. R., Takado, Y., Salameh, N., Capozzi, A., Cheng, T., Hyacinthe, J.N., Mishkovsky, M., Roussel, C., Comment, A.(2013). Proceedings of the National Academy of Sciences, 110(45), 18064-18069.

Pulsatile blood flow in human bone assessed by laser-Doppler flowmetry and the interpretation of photoplethysmographic signals.

Binzoni, T., Tchernin, D., Hyacinthe, J.-N., Van De Ville, D., Richiardi, J.(2013). Physiol Meas, 34(3), N25-40.

http://stacks.iop.org/0967-3334/34/i=3/a=N25?key=crossref.17f52a372824595c2388332807e870da

ARFI-prepared MRgHIFU in liver: simultaneous mapping of ARFI-displacement and temperature elevation, using a fast GRE-EPI sequence.

Auboiroux, V., Viallon, M., Roland, J., Hyacinthe, J.N., Petrusca, L., Morel, D. R., Goget, T., Terraz, S., Gross, P., Becker, C. D., Salomir, R.(2012). Magnetic Resonance in Medicine , 68(3), 932-946.

http://doi.wiley.com/10.1002/mrm.23309

Haemodynamic responses to temperature changes of human skeletal muscle studied by laser-Doppler flowmetry.

Binzoni, T., Tchernin, D., Richiardi, J., Van De Ville, D., Hyacinthe, J.N.(2012). Physiological Measurement, 33(7), 1181-1197.

http://stacks.iop.org/0967-3334/33/i=7/a=1181?key=crossref.d0cbe11047ab103495d7fcecff248d7b

High time-resolved cardiac functional imaging using temporal regularization for small animal on a clinical 3T scanner.

Delattre, B. M. A., Van De Ville, D., Braunersreuther, V., Pellieux, C., Hyacinthe, J.N., Lerch, R., Mach, F., Vallee, J.P.(2012). IEEE Transactions on Biomedical Engineering, 59(4), 929-935.

http://ieeexplore.ieee.org/lpdocs/epic03/wrapper.htm?arnumber=6068237

Manganese kinetics demonstrated double contrast in acute but not in chronic infarction in a mouse model of myocardial occlusion reperfusion.

Delattre, B. M. A., Braunersreuther, V., Gardier, S., Hyacinthe, J.N., Crowe, L. A., Mach, F., Vallee, J.P.(2012). NMR in Biomedicine, 25(4), 489-497.

http://doi.wiley.com/10.1002/nbm.1759

Matching between regional coronary vasodilator capacity and corresponding circumferential strain in individuals with normal and increasing body weight.

Vincenti, G. M., Ambrosio, G., Hyacinthe, J.N., Quercioli, A., Seimbille, Y., Mach, F., Ratib, O., Vallee, J.P., Schindler, T. H.(2012). Journal of Nuclear Cardiology, 19(4), 693-703.

Assessment of left ventricular apical rotation in obese by Cardiovascular MR tagging

Vincenti, G. M., Hyacinthe, J.-N., Kuijer, J. P.A., Mach, F., Ratib, O., Schindler, T., Vallée, J.-P.(2011). Journal of Cardiovascular Magnetic Resonance, 13(1), 1.

Magnetic resonance imaging of post-systolic shortening in a closed-chest rat model of coronary occlusion using myocardial tagging

Gardier, S., Hyacinthe, J.-N., Jorge-Costa, M., Morel, D. R., Vallée, J.-P.(2011). Journal of Cardiovascular Magnetic Resonance, 13(1), 1.

Real time cardiac MRI: spline-based spatio-temporal reconstruction of spiral data

Delattre, B. M.A., Hyacinthe, J.-N., Krüger, G., Vallée, J.-P., Van De Ville, D.(2011). Journal of Cardiovascular Magnetic Resonance, 13(1), 1.

Spiral demystified

Delattre, B. M. A., Heidemann, R. M., Crowe, L. A., Vallee, J.P., Hyacinthe, J.N.(2010). Magnetic Resonance Imaging, 28(6), 862-881.

Hyperpolarizing gases via dynamic nuclear polarization and sublimation.

Comment, A., Jannin, S., Hyacinthe, J.-N., Miéville, P., Sarkar, R., Ahuja, P., Vasos, P. R., Montet, X., Lazeyras, F., Vallée, J.-P., Hautle, P., Konter, J. A., van den Brandt, B., Ansermet, J.-Ph., Gruetter, R., Bodenhausen, G.(2010). Physical Review Letters, 105(1), 018104.

Myocardial infarction quantification with Manganese-Enhanced MRI (MEMRI) in mice using a 3T clinical scanner.

Delattre, B. M. A., Braunersreuther, V., Hyacinthe, J.N., Crowe, L. A., Mach, F., Vallee, J.P.(2010). NMR in Biomedicine, 23(5), 503-513.

http://doi.wiley.com/10.1002/nbm.1489

The role of imaging and molecular imaging in the early detection of metabolic and cardiovascular dysfunctions.

Montet-Abou, K., Viallon, M., Hyacinthe, J.-N., Delattre, B., Vallee, J.-P., Didier, D., Croisille, P., Montet, X.(2010). International Journal of Obesity, 34 Suppl 2, S67-81.

http://www.nature.com/doifinder/10.1038/ijo.2010.242

In vivo labelling of resting monocytes in the reticuloendothelial system with fluorescent iron oxide nanoparticles prior to injury reveals that they are mobilized to infarcted myocardium.

Montet-Abou, K., Daire, J.L., Hyacinthe, J.N., Jorge-Costa, M., Grosdemange, K., Mach, F., Petri-Fink, A., Hofmann, H., Morel, D. R., Vallee, J.P., Montet, X.(2010). European Heart Journal, 31(11), 1410-1420.

SNR enhancement of highly-accelerated real-time cardiac MRI acquisitions based on non-local means algorithm.

Naegel, B., Cernicanu, A., Hyacinthe, J.N., Tognolini, M., Vallee, J.P.(2009). Medical Image Analysis, 13(4), 598-608.

Feasibility of complementary spatial modulation of magnetization tagging in the rat heart after manganese injection.

Hyacinthe, J.-N., Ivancevic, M. K., Daire, J. L., Vallee, J.-P.(2008). NMR in Biomedicine
, 21(1), 15-21.

http://doi.wiley.com/10.1002/nbm.1144

In vivo myocardial infarct area at risk assessment in the rat using manganese enhanced magnetic resonance imaging (MEMRI) at 1.5T.

Daire, J. L., Hyacinthe, J.-N., Tatar, I., Montet-Abou, K., Ivancevic, M. K., Masterson, K., Jorge-Costa, M., Morel, D. R., Vallee, J.-P.(2008). Magnetic Resonance in Medicine, 59(6), 1422-1430.

http://doi.wiley.com/10.1002/mrm.21493

Cine and tagged cardiovascular magnetic resonance imaging in normal rat at 1.5 T: a rest and stress study.

Daire, J.-L., Jacob, J.-P., Hyacinthe, J.-N., Croisille, P., Montet-Abou, K., Richter, S., Botsikas, D., Lepetit-Coiffe, M., Morel, D. R., Vallee, J.-P.(2008). Journal of Cardiovascular Magnetic Resonance, 10(1), 48.

http://jcmr-online.biomedcentral.com/articles/10.1186/1532-429X-10-48

High-resolution complementary spatial modulation of magnetization (CSPAMM) rat heart tagging on a 1.5 Tesla Clinical Magnetic Resonance System: a preliminary feasibility study.

Ivancevic, M. K., Daire, J.-L., Hyacinthe, J.-N., Crelier, G., Kozerke, S., Montet-Abou, K., Gunes-Tatar, I., Morel, D. R., Vallee, J.-P.(2007). Investigative Radiology, 42(3), 204-210.

http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:landingpage&an=00004424-200703000-00008

Extrema temporal chaining: A new method for computing the 2D-displacement field of the heart from tagged MRI

Jacob, J.-P., Vachier, C., Morel, J.-M., Daire, J.-L., Hyacinthe, J.-N., Vallee, J.-P.(2006). Advanced Concepts for Intelligent Vision Systems, Proceedings, 4179, 897-908.

Optimization of cardiac cine in the rat on a clinical 1.5-T MR system.

Montet-Abou, K., Daire, J. L., Ivancevic, M. K., Hyacinthe, J.-N., Nguyen, D., Jorge-Costa, M., Morel, D. R., Vallee, J.-P.(2006). Magnetic Resonance Materials in Physics, Biology and Medicine, 19(3), 144-151.

http://link.springer.com/10.1007/s10334-006-0037-z